NAD+ Buffer — Nicotinamide Adenine Dinucleotide
NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme present in all living cells, serving as a critical electron carrier in metabolic redox reactions. As a central molecule in cellular energy production, DNA repair, and epigenetic regulation, NAD+ has become a focal point of longevity and mitochondrial research.
Biological Significance
NAD+ participates in over 500 enzymatic reactions and serves as a substrate for three major enzyme families: sirtuins (SIRT1-7), poly-ADP-ribose polymerases (PARPs), and cyclic ADP-ribose synthases (CD38/CD157). Sirtuin activation through NAD+ availability regulates mitochondrial biogenesis, oxidative stress defense, and inflammatory gene expression. Age-related NAD+ decline is associated with diminished mitochondrial function and altered cellular homeostasis.
Research Applications
- Mitochondrial function and biogenesis studies
- Sirtuin pathway activation and longevity research
- Cellular energy metabolism and ATP production
- DNA repair mechanism (PARP) investigations
- Age-related metabolic decline research
- Circadian rhythm and NAD+ oscillation studies
Product Specifications
- Quantity:Â 1000mg per vial
- Purity: ≥99% (verified)
- Form:Â Buffered solution
- Storage:Â Store in cool, dry place; refrigerate after reconstitution
- Testing:Â USA lab tested, COA available
For research purposes only. Not for human use or consumption.
